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國立陽明大學生理學科暨研究所
歡迎來到國立陽明大學生理學科暨研究所
黃志賢

個人資料  研究方向  代表著作 五年內執行計畫 實驗室成員   (2016.03.15  update)  

姓名

黃志賢

黃志賢

 
職稱   

合聘教授

通訊電話

(02)28757519ext307

傳真號碼

(02)28757540

電子信箱  jshuang@vghtpe.gov.tw          
學歷

1995/9-2000/12   醫學博士   國立陽明大學醫學院臨床醫學研究所

1982/9-1989/06   醫學士     中國醫藥大學醫學系 

經歷 2011/2-迄今   國立陽明大學醫學院醫學系泌尿學科 教授

2009/08-迄今  台北榮民總醫院教學研究部 醫學教育中心臨床教學科主任

2007/1-迄今   台北榮民總醫院外科部 教學主任 

2006/8-迄今   國立陽明大學醫學院醫學系 副系主任 

2003/8-2011/1 國立陽明大學醫學院醫學系泌尿學科 副教授

2000/2-2003/7 國立陽明大學醫學院醫學系泌尿學科 助理教授 

1997/7-1998/8 Baylor College of Medicine Scott Department of  Urology,  

                            Postdoctoral Fellow

1994/7-迄今  台北榮民總醫院外科部泌尿外科 主治醫師

1993/7-1994/6 台北榮民總醫院外科部泌尿外科 住院總醫師

1989/9-1993/6 台北榮民總醫院外科部 住院醫師 top  

 研究方向
           我的研究興趣在生殖內分泌、男性學及造精過程的調控。我的實驗室重點在應用動物模式及特定的荷爾蒙異常狀態的研究,來探討臨床上男性不孕症的問題。最近的主題著重於高泌乳素血症如何影響男性生殖功能。 

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代表著作

 

1.

Chen M, Huang YC, Yang S, Hsu JM, Chang YH, Huang WJ, Chen YM.. Common variants at 8q24 are associated with prostate cancer risk in Taiwanese men. Prostate 2010; 70(5):502-507 (SCI).

2.

Huang WJ, Yang LY, Pu HF, Tsai YT, Wang PS. The effects of anti-TNF-α antibody on hyperprolactinemia -related suppression of hCG-induced testosterone release in males rats. Journal of Sexual Medicine 2010;: (SCI).

3.

Hsiao FY, Huang WJ, Chen KK. The exposure of urologists and the treatment for male factor infertility on the websites of ART centers in Taiwan. Journal of Andrology 2010; 32(2):155-8 (SCI).

4.

Lin CC, Huang WJ, Chen KK. Measurement of testicular volume in smaller testes: how accurate is the conventional orchidometer? Journal of Andrology 2010; 30(6):685-689 (SCI).

5.

Cho YM, Pu HF, Huang WJ, Ho LT, Wang SW, Wang PS. Role of Serum- and Glucocorticoid-Inducible Kinase-1 in Regulating Torsion-Induced Apoptosis in Rats. International Journal of Andrology 2011 Aug; 34(4):379-89. (SCI).

6.

Lin YS, Chung HK, Lin ATL, Huang WJ, Huang YH, Lin TP, Chen KK. Laparoscopic partial nephrectomy: Taipei Veterans General Hospital experience. Journal of the Chinese Medical Association 2010; 73(4):194-198 (SCI).

7.

Chen SS, Huang WJ. Differences in biochemical markers and body mass index between patients with and without varicocele. Journal of the Chinese Medical Association 2010; 73(4):194-198 (SCI).

8.

Chen SS, Huang WJ. Experience of Varicocele Management During Ipsilateral Inguinal Herniorrhaphy: A Prospective Study. Journal of the Chinese Medical Association 2010; 73(5):248-251 (SCI).

9.

Huang WJ, Lin YW, Hsiao KN, Eilbe KS, Salido EC, Yen PH. Restricted expression of the human DAZ protein in premeiotic germ cells. Human Reproduction 2009; 23:1280-1289 (SCI).

10.

Chen M, Huang YC, Ko IL, Yang S, Chang YH, Huang WJ, Chen YM.. The rs1447295 at 8q24 is a risk variant for prostate cancer in Taiwanese men. Urology 2009; 74(3):698-701 (SCI).

11.

Lin CC, Huang WJ, Chen KK. Measurement of testicular volume in smaller testes: how accurate is the conventional orchidometer? Journal of Andrology 2009; 30(6):685-689 (SCI).

12.

Huang WJ, Yen PH. Genetics of spermatogenic failure. Sexual Development 2008; 2:251-9 (SCI).

13.

Chen SS, Huang WJ, Chang LS, Wei YH. Attenuation of oxidative stress after varicocelectomy in subfertile patients with varicocele. Journal of Urology 2008; 179(2):639-42 (SCI).

14.

Lin CC, Huang WJ, Wu LJ, Chang YH, Lin AT, Chen KK.. Diagnosis of prostate cancer: repeated transrectal prostate biopsy or transurethral resection. Journal of the Chinese Medical Association 2008; 71(9):448-454 (SCI).

15.

Fan YH, Chang YH, Huang WJ, Chung HJ, Chen KK. Renal oncocytoma: clinical experience of Taipei Veterans General Hospital. Journal of the Chinese Medical Association 2008; 71(5):254-258 (SCI).

16.

Huang YC, Lee CM, Chen M, Chung MY, Chang YH, Huang WJ, Ho DM, Pan CC, Wu TT, Yang S, Lin MW, Hsieh JT, Chen YM.. Haplotypes, loss of heterozygosity, and expression levels of glycine N-methyltransferase in prostate cancer. Clinical Cancer Research 2007; 13(5):1412-20 (SCI).

17.

Huang WJ. ATP and spinal cord injury-related neurogenic bladder. Journal of the Chinese Medical Association 2007; 70(10):433-434 (SCI). (Impact factor:0.678; Rank:62.3%)

18.

Lin YH, Chung HJ, Lin AT, Chang YH, Huang WJ, Hsu YS, Chang SC, Chen KK. Complications of pure transperitoneal laparoscopic surgery in urology: the Taipei Veterans General Hospital experience. Journal of the Chinese Medical Association 2007; 70(11):481-485 (SCI).

19.

Tsai HW, Huang WJ, Chen CY, Chiang MM, Chao KC, Shen SH, Hung JH, Chen YJ. Two- and three-dimensional transvaginal Doppler ultrasound analysis of urethral clear cell carcinoma. Ultrasound in Obstetrics & Gynecology 2007; 29(6):713-716 (SCI).

20.

Huang YC, Chen M, Lin MW, Chung MY, Chang YH, Huang WJ, Wu TT, Hsu JM, Yang S, Chen YM.. CYP19 TCT tri-nucleotide Del/Del genotype is a susceptibility marker for prostate cancer in a Taiwanese population. Urology 2007; 69(5):996-1000 (SCI).

21.

Lin YW, Chia-Ling Hsu L, Kuo PL, Huang WJ, Chiang HS, Yeh SD, Hsu TY, Yu YH, Hsiao KN, Cantor RM, Yen PH. Partial duplication at AZFc on the Y chromosome is a risk factor for impaired spermatogenesis in Han Chinese in Taiwan. Human Mutation 2007; 28: (SCI).

22.

Chang YL, Lin AT, Chen KK, Chang YH, Wu HH, Kuo JY, Huang WJ, Lu SH, Hsu YS, Chung HJ, Chang SC.. Correlation between serum prostate specific antigen and prostate volume in Taiwanese men with biopsy proven benign prostatic hyperplasia. Journal of Urology 2006; 176:196-9 (SCI).

23.

Lin YH, Huang WJ, Chen KK. Using stainless steel chopstick for self-performing urethral sounding in preventing recurrence of anterior urethral stricture. Journal of the Chinese Medical Association 2006; 69:189-92 (SCI).

24.

Ng YY, Shen SH, Huang WJ. Chronic pyonephrosis with polycystic change. Nephrology 2005; 10:422-3 (SCI).

25.

Lin TP, Huang WJ, Chen KK. Differentiation of benign prostatic hyperplasia from prostate cancer using prostate specific antigen dynamic profile after transrectal prostate biopsy. Journal of Urology 2004; 171:2226-9 (SCI).

26.

Chen SS, Huang WJ, Chang LS, Wei YH. 8-Hydroxy-2'-deoxyguanosine in leukocyte DNA of spermatic vein as a biomarker of oxidative stress in patients with varicocele. Journal of Urology 2004; 172:1418-21 (SCI).

27.

Kan SF, Huang WJ, Lin LC, Wang PS. Inhibitory effects of evodiamine on the growth of human prostate cancer cell line LNCaP. International Journal of Cancer 2004; 110(5:641-51 (SCI).

28.

Lin TP, Pan CC, Huang WJ, Murphy GF. Primary sweat gland carcinosarcoma of the scrotal skin. Journal of Cutaneous Pathology 2004; 31(10):678-82 (SCI).

29.

Lin YM, Huang WJ, Lin JSN, Kuo PL. Progressive depletion of germ cells in a man with non-mosaic Klinefelter’s syndrome: optimal time for sperm recovery . Urology 2004; 63(2):380-1 (SCI).

30.

Tung MT, Huang WJ, Chen KK. Experiences of techiniques of a modifined subinguinal varicocelectomy for painful varicocele and varicocele-associated infertility. Journal of the Chinese Medical Association 2004; 67:296-300 (SCI).

31.

Sheu JY, Chung HJ, Chen KK, Lin AT, Chang YH, Wu HH, Huang WJ, Hsu YS, Kuo JY, Chang LS. Lymphangioma of male exogenital organs. Journal of the Chinese Medical Association 2004; 67:204-6 (SCI).

32.

Yang LY, Huang WJ, Hsieh HG, Lin CY. H1-A extracted from Cordyceps sinensis suppresses the proliferation of human mesangial cells and promotes apoptosis, probably by inhibiting the tyrosine phosphorylation of Bcl-2 and Bcl-XL. Journal of Laboratory and Clinical Medicine 2003; 141(1):74-83 (SCI).

33.

Hsu YS, Huang WJ, Kuo JY, Chung HJ, Chen KK, Chang LS. Experience of surgical treatment of Peyronie’s disease with deep dorsal venous patch graft in Taiwanese men. Journal of the Chinese Medical Association 2003; 66(8):487-491 (SCI).

34.

Sheu JY, Chen KK, Lin AT, Chang YH, Wu HH, Huang WJ, Hsu YS, Kuo JY, Chung HJ, Chang LS. Long-term efficacy and safety of sildenafil for patients with erectile dysfunction. Journal of the Chinese Medical Association 2003; 66(8):480-6 (SCI).

35.

Huang WJ, Yeh JY, Kan SF, Chang LS, Wang PS. Role of testicular interstitial macrophages in regulating testosterone release in hyperprolactinemia J Cell Biochem. Journal of Cellular Biochemistry 2003; 88(4):766-773 (SCI).

36.

Yeh JY, Huang WJ, Kan SF, Wang PS. Effects of bufalin and cinobufagin on the proliferation of androgen dependent and independent prostate cancer cells. Prostate 2003; 54(2):112-124 (SCI).

37.

Lin TP, Hsu YS, Chen KK, Lin AT, Chang YH, Wu HH, Huang WJ, Kuo JY, Chung HJ, Chang LS. Chyluria--experience of Taipei Veterans General Hospital. Journal of the Chinese Medical Association 2003; 66(2):109-112 (SCI).

38.

Lin AD, Chen KK, Lin AT, Chang YH, Wu HH, Kuo JY, Huang WJ, Hsu YS, Chung HJ, Chang LS. Antiandrogen-associated hepatotoxicity in the management of advanced prostate cancer. Journal of the Chinese Medical Association 2003 Dec; 66(12):735-40 (SCI).

39.

Yang MH, Chen KK, Yen CC, Wang WS, Chang YH, Huang WJ, Fan FS, Chiou TJ, Liu JH, Chen PM H. Unusually high incidence of upper urinary tract urothelial carcinoma in Taiwan Urology. Urology 2002; 59:681-687 (SCI).

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五年內執行計畫

 

2011/08/01~2012/07/31 

泌乳素及抗腫瘤壞死因子對雄性生殖功能與生殖細胞凋亡及自嗜作用的影響

國科會

2010/08/01~2011/07/31 

建立以睪丸組織抹片鑑定分化中之各級生殖細胞之方法以應用於顯微睪丸精子萃取手術(2/2) 

國科會

2009/08/01~2010/07/31 

建立以睪丸組織抹片鑑定分化中之各級生殖細胞之方法以應用於顯微睪丸精子萃取手術(1/2)

國科會

2007/08/01~2008/07/31

高泌乳素血症雄鼠之精細胞凋亡與濾泡激素調控的關係 

國科會 

2007/08/01~2008/08/31

DAZ基因功能性的分析(3/3) 

國科會 

2011/01/01~2011/12/31

外科部臨床醫師資培育整合計畫 

台北榮總 

2011/01/01~2011/12/31

高泌乳素血症雄鼠生殖功能探討(2) 

台北榮總 

2011/01/01~2011/12/31

教學訓練專案計畫子計畫-2 

台北榮總 

2010/01/01~2010/12/31

實證醫學教學研究推動計畫 

台北榮總 

2010/01/01~2010/12/31

高泌乳素血症雄鼠的生殖功能 

台北榮總 

2010/01/01~2010/12/31

外科部整合臨床師資培育計畫 

台北榮總 

2009/01/01~2009/12/31

高泌乳素血症精原母細胞凋亡之誘發與腫瘤壞死因子的關係 

台北榮總 

2009/01/01~2009/12/31

外科臨床教師之訓練計劃與成效評估 

台北榮總 

2008/01/01~2008/12/31

泌尿外科臨床教學評量 

台北榮總 

2008/01/01~2008/12/31

誘發高泌乳素血症雄鼠生殖細胞凋亡機轉研究 

台北榮總 

2008/01/01~2008/12/31

睪丸睪固酮濃度之種族間差異 

台北榮總 

2007/01/01~2007/12/31

泌尿外科教師發展訓練計畫 

台北榮總 

2007/01/01~2007/12/31

睪丸內巨噬細胞對造精過程的影響 top

台北榮總 

 

實驗室成員

博士班:王中麟 

研究助理:陳宇綮 李欣 黃詩方

博士後研究員:江怡德 

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